Mark W. Tibbitt

The paper introduces hydroMEA, a 3D hydrogel-based microfluidic device that enables real-time electrophysiological measurements of myelinated nerve-on-chip systems using human iPSC-derived neurons and Schwann cells.

This paper develops a hydrogel that enables subcutaneous delivery of vesicant antibody-drug conjugates by confining them in a depot, reducing tissue damage while maintaining antitumor efficacy.

This paper introduces an acoustofluidic device to improve microtissue histology by pre-patterning microtissues in HistoGel, simplifying downstream processing and increasing efficiency.

This paper develops a method to create multi-scale vascular networks in hydrogels using volumetric bioprinting and phase separation, enabling capillary-like structures for nutrient delivery.

This paper develops a hydrogel platform for subcutaneous delivery of trastuzumab, achieving sustained release over 3 days in vitro and in vivo.

This paper develops tunable macroporous hydrogels via phase separation for cell culture, showing improved cell spreading and migration in porous systems.