Author
University of OxfordORCID 0000-0002-4921-7505Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Ekaterina Kot, Matteo Paolo Ferla, Patricia Helen Hollinshead…·F. von Delft
The paper solves the crystal structure of Arabidopsis thaliana FatA and identifies fragments that target novel regions, enabling the design of new herbicides with improved potency and novel interaction modes.
Matthew G Williamson, Rachel Heon‐Roberts, Sarah N. J. Franks…·Brent James Ryan
This study shows USP30 inhibition improves mitochondrial health through both PINK1-dependent and independent mechanisms, enhancing mitophagy and mitochondrial efficiency in neurons.
Darragh Patrick O'Brien, Hannah B. L. Jones, Yuqi Shi…·Benedikt Mathias Kessler
This study investigates the structural dynamics of USP30 inhibition by a covalent inhibitor, revealing its binding mechanism and selectivity advantages over non-covalent inhibitors.