Author

M. Ángeles Bonache

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-4922-5345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:electrophysiology· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Ángel OrteiD· 1 shared Ángel Pérez-LaraiD· 1 shared Ángela de Benito-BuenoiD· 1 shared Antonio Vicente Ferrer-MontieliD· 1 shared Asia M. Fernández-CarvajaliD· 1 shared Carmen ValenzuelaiD· 1 shared Carmen Viedma-Barba· 1 shared David CabañeroiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Ángel OrteORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Druggability of Phospholipase C-β Isoforms with Small Peptides Patterned after the Autoinhibitory XY Linker

Jorge de Andrés-López, David Cabañero, Isabel Devesa, Shihab S. Shah, Gregorio J. Fernandez-Ballester, Nikita L. Gamper, M. Ángeles Bonache, Rosario González‐Muñiz, Asia M. Fernández-Carvajal, Antonio Vicente Ferrer-Montiel

The paper identifies peptides based on the autoinhibitory XY linker of PLCβ isoforms that inhibit PLCβ activity and reduce inflammation and pain in a mouse model.

bioRxiv · Jul 22, 2025 · PreprintMolecular Biology

IQM-22110 as a selective KV4.3/KChIP3 modulator. Molecular determinants of the KChIP3 binding site

Paula G. Socuéllamos, Carmen Viedma-Barba, Ángela de Benito-Bueno, M. Ángeles Bonache, Maria Ropero, Sara Diez, Pablo Elizalde, Irene Marín-Olivero, Maria Redondo, José R. Naranjo, Juan Antonio Gonzalez‐Vera, Ángel Orte, Ángel Pérez-Lara, Mercedes Martín‐Martinez, Carmen Valenzuela, Marta Gutiérrez‐Rodríguez

This study identifies IQM-22110 as a selective KV4.3/KChIP3 modulator, showing it binds specifically to KV4.3/KChIP3 and not KV4.3/KChIP2 or KV4.3 alone.

bioRxiv · May 29, 2025 · PreprintPharmacology & Toxicology