Author

Hsiang‐Chih Lu

Baylor College of MedicineORCID 0000-0002-4927-4577Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Akash J. PateliD· 1 shared Akdes Serin HarmancıiD· 1 shared Albert H. KimiD· 1 shared Alicia Yang· 1 shared Allegra A. PettiiD· 1 shared Amanda M BrowniD· 1 shared Bhuvic PateliD· 1 shared Cheryl BrandenburgiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Akash J. PatelORCID

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2 papers

Recent·Most cited

Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice

Sarah G Donofrio, Cheryl Brandenburg, Amanda M Brown, Tao Lin, Hsiang‐Chih Lu, Roy V. Sillitoe

The paper shows that Purkinje cell loss in aged mice occurs in parasagittal stripes and is linked to motor dysfunction, with similar patterns observed in human postmortem samples.

eLife · Dec 1, 2025Peer-reviewedNeuroscience

NF2 Loss-of-Function and Hypoxia Drive Radiation Resistance in Grade 2 Meningiomas

Bhuvic Patel, Sangami Pugazenthi, Collin William English, Vijay Nitturi, Shree S. Pari, Tatenda Mahlokozera, William A. Leidig, Hsiang‐Chih Lu, Alicia Yang, Kaleigh F. Roberts, Patrick DeSouza, Kyle P. McGeehan, Diane D. Mao, Namita Sinha, Joseph E. Ippolito, , Albert H. Kim

This study identifies NF2 loss-of-function and hypoxia as drivers of radiation resistance in Grade 2 meningiomas through genetic, histopathological, and transcriptional analyses.

JNCI Journal of the National Cancer Institute · Jan 27, 2025Peer-reviewedMolecular Biology