ImmunologyArthritis & RheumatologyPeer-reviewed
Loss of TRIM21 drives UVB-induced systemic inflammation by regulating DNA-sensing pathways
Gantsetseg Tumurkhuu, Graziela Perri, Richard Moore…·Caroline Anne Jefferies
This study shows that loss of TRIM21 increases UVB-induced systemic inflammation by enhancing IFN expression through impaired STING signaling in mice.
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