Author

Travis Ptacek

University of North Carolina at Chapel HillORCID 0000-0002-4949-0149Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeremy M. SimoniD· 2 shared Adriana S. BeltrániD· 1 shared Albert J. KeungiD· 1 shared Dilara SeniD· 1 shared Guang Ken Lin· 1 shared Jeremy E. PurvisiD· 1 shared Katarzyna M. KedzioraiD· 1 shared Margaret A. RedickiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersDevelopmental Biology

Jeremy M. SimonORCID

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2 papers

Recent·Most cited

Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids

R. Chris Estridge, Z. Begum Yagci, Dilara Sen, Travis Ptacek, Jeremy M. Simon, Albert J. Keung

This study shows that UBE3A loss affects both neuronal and non-neuronal cells in human cerebral organoids, altering cell composition and transcriptomes.

bioRxiv · Feb 9, 2024 · PreprintDevelopmental Biology

Single-cell dynamics of core pluripotency factors in human pluripotent stem cells

Sonja Mihailovic, Samuel C. Wolff, Katarzyna M. Kedziora, Nicole M. Smiddy, Margaret A. Redick, Yuli Wang, Guang Ken Lin, Tarek M. Zikry, Jeremy M. Simon, Travis Ptacek, Nancy L. Allbritton, Adriana S. Beltrán, Jeremy E. Purvis

This study uses CRISPR/Cas9 and microraft arrays to track OCT4, SOX2, and NANOG dynamics in human stem cells during differentiation, revealing spatiotemporal patterns in germ layer formation.

bioRxiv · Dec 13, 2022 · PreprintDevelopmental Biology