Chiara Salio

C-LTMRs Regulate Thermosensation and Gate the Transition from Acute to Chronic Pain

This study shows that C-LTMRs regulate thermosensation and are critical for resolving pain after injury, as their ablation leads to persistent hypersensitivity and altered transcriptional responses.

Gut microbiota promotes pain chronicity in Myosin1A deficient male mice

The paper shows that dysbiotic gut microbiota in Myosin1A-deficient male mice promotes chronic pain by sustaining DRG inflammation, which is reversible with antibiotic treatment.

Intrinsic microtubule destabilization of multiciliated choroid plexus epithelial cells during postnatal lifetime

The paper shows that choroid plexus cilia undergo axoneme resorption through microtubule destabilization, controlled by polyglutamylation and spastin, and is conserved in human samples.