Elisa D’Este

This study identifies Paralemmin-2 as a component of axon initial segments and nodes of Ranvier, showing its role in modulating the submembrane cytoskeleton and neuronal excitability.

This study identifies Paralemmin-1 as a regulator of the neuronal submembrane cytoskeleton MPS, showing it enhances periodicity and is essential for its structure and function.

This study uses computational modeling to show that protein concentration and binding strength variations control cluster formation in synapses, with simulations matching experimental data on PSD95 localization.

This paper introduces a novel mouse reporter line for live imaging of axon initial segments, enabling real-time study of AIS plasticity in vivo.

This study uses MINFLUX to track dynein movement in live neurons, revealing 8 nm steps and rapid direction reversals, suggesting a single ATP-dependent stepping mechanism.

The paper shows that choroid plexus cilia undergo axoneme resorption through microtubule destabilization, controlled by polyglutamylation and spastin, and is conserved in human samples.

This study uses advanced imaging techniques to show how synaptic activity affects the incorporation of newly translated PSD-95 into synaptic clusters at near-molecular resolution.

This study quantifies neurofilament isoforms at postsynapses using STED nanoscopy and links their presence to synaptic strength and activity markers.