Cancer BiologybioRxivPreprint
Pan-cancer 3D genomic analysis revealed extremely long Polycomb loops as the biomarker for sensitivity to Polycomb inhibition
Sean Moran, Zhong Fan, Miriam Zanovello…·Xiaotian Zhang
The paper identifies long Polycomb loops as a biomarker for sensitivity to Polycomb inhibition in certain cancers, particularly in AMLs with specific mutations.