Author

Alison H. Affinati

University of MichiganORCID 0000-0002-4967-9240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Abigail J. TomlinsoniD· 3 shared Martin Grosvenor MyersiD· 3 shared Alan C. RuppiD· 2 shared Cadence A. TrueiD· 2 shared Chien LiiD· 2 shared David P. OlsoniD· 2 shared Melissa Ann KirigitiiD· 2 shared Paul KievitiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Abigail J. TomlinsonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Control of Physiologic Glucose Homeostasis via the Hypothalamic Modulation of Gluconeogenic Substrate Availability

Jiaao Su, Abdullah Hashsham, Nandan Kodur, Carla Burton, Amanda Mancuso, Anjan Singer, Jennifer Wloszek, Abigail J. Tomlinson, Warren T. Yacawych, Jonathan N. Flak, Kenneth T. Lewis, Lily R. Oles, Hiroyuki Mori, Nadejda Bozadjieva-Kramer, Adina F. Turcu, , Alison H. Affinati

The paper identifies VMNCckbr neurons that regulate fasting blood glucose by enhancing adipose tissue lipolysis and substrate release via the sympathetic nervous system.

Molecular Metabolism · Jul 18, 2025Peer-reviewedPhysiology

Leptin-mediated suppression of food intake by conserved Glp1r-expressing neurons prevents obesity

Alan C. Rupp, Abigail J. Tomlinson, Alison H. Affinati, Cadence A. True, Sarah Rene Lindsley, Melissa Ann Kirigiti, Alexander MacKenzie, Chien Li, Lotte Bjerre Knudsen, David P. Olson, Paul Kievit, Martin Grosvenor Myers

The paper identifies a conserved population of GABAergic Glp1r-expressing LepRb neurons that mediate leptin's suppression of food intake and prevention of obesity.

bioRxiv · Dec 10, 2021 · PreprintNeuroscience

Cross-Species Analysis Defines the Conservation of Anatomically-Segregated VMH Neuron Populations

Alison H. Affinati, Paul V. Sabatini, Cadence A. True, Abigail J. Tomlinson, Melissa Ann Kirigiti, Sarah Rene Lindsley, Chien Li, David P. Olson, Paul Kievit, Martin Grosvenor Myers, Alan C. Rupp

The paper identifies conserved VMH neuron populations across species using TRAP-seq and snRNA-seq data, defining six major neuron classes with distinct anatomical and genetic features.

eLife · May 21, 2021Peer-reviewedNeuroscience