Paul V. Sabatini

The paper identifies distinct subpopulations of LeprGlp1r neurons that separately control food intake and blood pressure.

The paper creates a multi-species DVC cell atlas using snRNAseq, identifying cell types and novel populations in mouse and rat.

This paper develops a genetically encoded melanocortin sensor, FLAREMC, for high sensitivity intravital imaging of melanocortin signaling in vivo.

The paper creates a cross-species atlas of the dorsal vagal complex using single-nucleus RNA sequencing and spatial profiling, revealing molecular mechanisms of cagrilintide's effects on energy balance.

The paper identifies GFRAL expression in the caudal brainstem and shows minimal expression in peripheral tissues in mice and humans.

This study shows that methamphetamine exposure in mice induces infradian locomotor rhythms and mania-like behaviors, which depend on dopamine neurons projecting to the nucleus accumbens.

The paper identifies conserved VMH neuron populations across species using TRAP-seq and snRNA-seq data, defining six major neuron classes with distinct anatomical and genetic features.

This study identifies GFRAL-expressing neurons in the hindbrain that suppress food intake through aversive pathways by responding to non-meal-related signals.