Jingyue Ju

Copper-Free Click Chemistry Enables High-Fidelity Engineering of Mitochondria Targeted Brain-Derived Exosomes

This paper uses copper-free click chemistry to engineer mitochondria-targeted brain-derived exosomes, preserving their structure and function while enabling targeted delivery and imaging.

A Reversible Mitochondrial ROS Probe for Monitoring Mitophagy Dynamics: Development and Application of MitoFlare

The paper introduces MitoFlare, a reversible mitochondrial ROS probe, and demonstrates its application in quantifying mitophagy dynamics in real time using a dual-probe imaging platform.

A Novel Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging in Neurotoxic Conditions and In Vivo Brain Studies

This paper introduces a novel mitochondrial-targeting dye, Cy5-PEG4, for in vivo brain imaging and neurodegenerative disease studies, showing improved BBB penetration and reduced toxicity.

Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase

This study shows that three nucleotide analogues inhibit SARS-CoV-2 polymerase by being incorporated and blocking further RNA synthesis.