Author

Jamie L. Grit

Van Andel InstituteORCID 0000-0002-5002-2940Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Carrie R. GraveeliD· 2 shared Curt J. EssenburgiD· 2 shared Marie AdamsiD· 2 shared Matthew R. SteensmaiD· 2 shared Angela C. HirbeiD· 1 shared Anwesha DeyiD· 1 shared Benjamin K. JohnsoniD· 1 shared Christine A. PratilasiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Carrie R. GraveelORCID

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2 papers

Recent·Most cited

YAP signaling promotes resistance to MEK and AKT inhibition in NF1-related MPNSTs

Lauren E. McGee, Jamie L. Grit, Curt J. Essenburg, Sophia Agrusa, Elizabeth A. Tovar, Lisa Turner, Katelyn Becker, Jason Zbieg, Anwesha Dey, Jennifer E. Klomp, Jeffrey A. Klomp, Marie Adams, Ian Beddows, Emily Wolfrom, Zhen Fang Fu, , Matthew R. Steensma

This study identifies YAP signaling as a driver of resistance to MEK and AKT inhibitors in NF1-related MPNSTs using preclinical models and spatial transcriptomics.

bioRxiv · Jun 16, 2025 · PreprintCancer Biology

Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/P38 signaling

Jamie L. Grit, Benjamin K. Johnson, Patrick S. Dischinger, Curt J. Essenburg, Marie Adams, Stacy Campbell, Kai Pollard, Christine A. Pratilas, Timothy J. Triche, Carrie R. Graveel, Matthew R. Steensma

This study identifies epigenetic differences between cutaneous and plexiform neurofibromas that drive distinct RAS/MKK/P38 signaling and clinical behavior.

Epigenetics & Chromatin · Jan 12, 2021Peer-reviewedGenomics