Author
Van Andel InstituteORCID 0000-0003-3586-8566Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Lauren E. McGee, Jamie L. Grit, Curt J. Essenburg…·Matthew R. Steensma
This study identifies YAP signaling as a driver of resistance to MEK and AKT inhibitors in NF1-related MPNSTs using preclinical models and spatial transcriptomics.
Naman Vatsa, Julia K. Brynildsen, Thomas M. Goralski…·Michael X. Henderson
The paper identifies group II p21-activated kinases as regulators of α-synucleinopathy by linking network vulnerability analysis to gene expression and pharmacological interventions.
Thomas M. Goralski, Lindsay K. Meyerdirk, Libby Breton…·Michael X. Henderson
The paper uses spatial transcriptomics to identify specific cortical neurons vulnerable to Lewy pathology in PD and discovers a conserved molecular dysfunction signature in both mice and humans.