Author

Hiroshi Akasaka

Iwate Medical UniversityORCID 0000-0003-0238-8320Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:polygenic risk· 1 Approach:statistical model· 1

Frequent Co-Authors

Akemi KakinoiD· 1 shared Atsushi ShimizuiD· 1 shared Cheng WangiD· 1 shared Hideki OhmomoiD· 1 shared Hikari Takeshita· 1 shared Hiromi RakugiiD· 1 shared Hiroshi Koriyama· 1 shared Jittoku Ihara· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Akemi KakinoORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJul 1, 2026

Polygenic Risk Score Stratification Guides Prioritization of Modifiable Risk Factors for Stroke Prevention

Yoichi Sutoh, Tsuyoshi Hachiya, Yayoi Otsuka‐Yamasaki…·Atsushi Shimizu

This study shows that modifiable risk factors have varying impacts on stroke risk depending on genetic predisposition, with higher genetic risk amplifying the effect of these factors.

DOI 10.64898/2026.06.28.26356786

humanelectronic health records

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Molecular BiologybioRxivMay 13, 2024

Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction

Jittoku Ihara, Yibin Huang, Yoichi Takami…·Koichi I. Yamamoto

This study shows oxLDL enhances Ang II-induced Gq signaling via the AT1-LOX1 complex, contributing to renal dysfunction in CKD and hypertension.

3 citations

mouseexperimental assay

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