Jennifer H. Haggarty

This study compares lipidomic profiles of Trypanosoma congolense and Trypanosoma brucei to understand their metabolic differences and implications for in vitro culture and therapy development.

This study identifies a metabolic-ageing profile in Atlantic salmon similar to humans and shows that spermidine supplementation reduces inflammation and improves metabolic flexibility in aged fish.

This study identifies Tfe2 as a novel antifungal effector that inhibits protein translation and hyperactivates TORC1, leading to cellular remodeling in yeast.

This study investigates the systemic effects of microbiome-derived carnitine analogues in mice, showing carnitine depletion and mitochondrial dysfunction due to inhibition of carnitine biosynthesis.

This paper develops a CRISPR base-editing library for genome-wide loss-of-function screening in Leishmania mexicana to study drug response mechanisms and identify novel biomarkers.

This study shows that rapamycin-induced autophagy enhances lipid breakdown and reduces lipotoxicity in Atlantic salmon cells.