Author

Miriam Hernandez-Meadows

Thomas Jefferson UniversityORCID 0000-0002-5063-0161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Ashley Coleman· 1 shared Hiromi SesakiiD· 1 shared John A. Collins· 1 shared Kameron L. Inguito· 1 shared Kimheak SaoiD· 1 shared Makarand V. RisbudiD· 1 shared Owen Haslam· 1 shared Paige K Boneski· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Ashley Coleman

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1 paper

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedJul 1, 2025

OPA1 protects intervertebral disc and knee joint health in aged mice by maintaining the structure and metabolic functions of mitochondria

Vedavathi Madhu, Miriam Hernandez-Meadows, Ashley Coleman…·Makarand V. Risbud

This study shows that OPA1 maintains mitochondrial structure and metabolic functions in NP cells and chondrocytes, preventing age-related degeneration in mouse intervertebral discs and knee joints.

42 citationstop 1%

mouseATAC-seq

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