Author

Leonie Schütz

RWTH Aachen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:DNA methylation· 3 Organism:human· 3 Organism:Arabidopsis· 1 Research Focus:differential expression· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Elmar G. WeinholdiD· 4 shared Sapir Margalit· 3 shared Yael Michaeli· 3 shared Yuval EbensteiniD· 3 shared Dmitry TorchinskyiD· 2 shared Gil Nifker· 2 shared Sigal Avraham· 2 shared Andreas Dankers· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersGenomics

Elmar G. WeinholdORCID

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4 papers

Recent·Most cited

Optical Genome and Epigenome Mapping of Clear Cell Renal Cell Carcinoma

Sapir Margalit, Zuzana Tulpová, Yael Michaeli, Tahir Detinis Zur, Jasline Deek, Sivan Louzoun Zada, Gil Nifker, Assaf Grunwald, Yuval Scher, Leonie Schütz, Elmar G. Weinhold, Yehudit Gnatek, Dorit Omer, Benjamin Dekel, Eitan Friedman, Yuval Ebenstein

The paper uses optical genome and epigenome mapping to identify somatic alterations in early-stage clear cell renal cell carcinoma, revealing both known and novel genomic and epigenomic changes.

NAR Cancer · Jan 15, 2025Peer-reviewedGenomics

A genetic circuit on a single DNA molecule as autonomous dissipative nanodevice

Ferdinand Greiss, Nicolas Lardon, Leonie Schütz, Yoav Barak, Shirley Shulman Daube, Elmar G. Weinhold, Vincent Noireaux, Roy Bar‐Ziv

The paper demonstrates a single DNA molecule-based genetic circuit that functions as a dissipative nanodevice by enabling coexpressional localization of proteins.

Nature Communications · Jan 29, 2024Peer-reviewedSynthetic Biology

Simultaneous global labeling (SiGL) of 5-methylcytosine and 5-hydroxymethylcytosine by DNA alkylation with a synthetic cofactor and engineered methyltransferase

Sigal Avraham, Leonie Schütz, Larissa Käver, Andreas Dankers, Sapir Margalit, Yael Michaeli, Shahar Zirkin, Dmitry Torchinsky, Noa Gilat, Omer Bahr, Gil Nifker, Maya Koren‐Michowitz, Elmar G. Weinhold, Yuval Ebenstein

The paper introduces a method to simultaneously analyze 5-methylcytosine and 5-hydroxymethylcytosine in clinical samples, showing reduced 5-hydroxymethylcytosine in colorectal cancer and chronic lymphocytic leukaemia.

bioRxiv · Oct 31, 2022 · PreprintGenetics

Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping

Tslil Gabrieli, Yael Michaeli, Sigal Avraham, Dmitry Torchinsky, Sapir Margalit, Leonie Schütz, Matyas Juhasz, Ceyda Çoruh, Nissim Arbib, Zhaohui Sunny Zhou, Julie A. Law, Elmar G. Weinhold, Yuval Ebenstein

This paper develops a chemoenzymatic method to label non-methylated CpGs in DNA, enabling single-molecule epigenetic profiling in human and plant genomes.

Nucleic Acids Research · Jun 3, 2022Peer-reviewedGenomics