Author

Katja Apelt

Leiden University Medical CenterORCID 0000-0002-5065-3785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Diana van den HeuveliD· 2 shared Martijn S. LuijsterburgiD· 2 shared Alfred C.O. VertegaaliD· 1 shared Anna E. HerlihyiD· 1 shared Annelotte P. WondergemiD· 1 shared Areetha D’SouzaiD· 1 shared Elisheva E. HeilbruniD· 1 shared George YakoubiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Diana van den HeuvelORCID

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2 papers

Recent·Most cited

STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair

Diana van den Heuvel, Marta Rodríguez‐Martínez, Paula J. van der Meer, Nicolás Nieto Moreno, Ji Young Park, Hyun-Suk Kim, Janne J. M. van Schie, Annelotte P. Wondergem, Areetha D’Souza, George Yakoub, Anna E. Herlihy, Krushanka Kashyap, Thierry Boissière, Jane Walker, Richard Mitter, , Martijn S. Luijsterburg

This study identifies STK19 as a factor facilitating the transition from initial TCR complex assembly to downstream repair steps by enabling RNAPII clearance.

Cell · Nov 14, 2024Peer-reviewedMolecular Biology

The sequential and cooperative action of CSB, CSA and UVSSA targets the TFIIH complex to DNA damage-stalled RNA polymerase II

Yana van der Weegen, Hadar Golan-Berman, Tycho E.T. Mevissen, Katja Apelt, Román González‐Prieto, Joachim Goedhart, Elisheva E. Heilbrun, Alfred C.O. Vertegaal, Diana van den Heuvel, Johannes C. Walter, Sheera Adar, Martijn S. Luijsterburg

This study defines the sequential and cooperative assembly mechanism of the TCR complex and reveals how TFIIH is recruited to DNA damage-stalled RNAPIIo.

Nature Communications · Apr 30, 2020Peer-reviewedMolecular Biology