Danny William Wilson

This paper identifies MMV006833 as an inhibitor of PfSTART1 in P. falciparum but shows it is ineffective against P. berghei due to structural differences and other factors.

This study shows that PfMSP2 modulates the susceptibility of merozoites to inhibitory antibodies targeting other invasion proteins, altering malaria vaccine strategies.

The paper identifies a conserved complex formed by PTRAMP, CSS, and Ripr in Plasmodium species that facilitates merozoite invasion of erythrocytes and shows its structural and functional conservation across species.

This study compares the roles of MSP4 and MSP5 in red blood cell invasion across malaria species, showing differential importance and highlighting MSP5 as a potential vaccine target for P. knowlesi and P. vivax.

This study shows that HOPS/CORVET complexes are essential for malaria parasite endocytosis and invasion organelle function, with distinct roles in different developmental stages.

This paper identifies a novel microtubule-associated protein, SPM3, essential for malaria parasite transmission by affecting gametocyte morphology and sporozoite motility.

This study identifies MMV020291 as a compound that targets actin-1/profilin dynamics in Plasmodium falciparum, inhibiting red blood cell invasion and apicoplast segregation.

The paper investigates six membrane transporters in Plasmodium falciparum, finding four essential for asexual development and one essential for gametocytogenesis.