Eli O. van der Sluis

This study designs and tests artificial FG-Nups to show that spacing and charge-to-hydrophobicity ratio affect Kap95 binding and transport selectivity through NPCs.

The study identifies two CTCF N-terminal motifs that synergistically stall cohesin-mediated DNA loop extrusion through distinct mechanisms.

The paper visualizes the biogenesis of a bacterial membrane protein using cryo-EM and cell-free synthesis, revealing a gate-independent insertion mechanism involving SecYEG and YidC.