Author

Anna G. Guzman

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alejandra G. Martell· 2 shared Josephine De La Fuente· 2 shared Margaret A. GoodelliD· 2 shared Abhishek MaitiiD· 1 shared Alex CaganiD· 1 shared An Q DinhiD· 1 shared Anja KarlstaedtiD· 1 shared Archish Anand· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

Alejandra G. Martell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nuclear Phase Separation Drives NPM1-mutant Acute Myeloid Leukemia

Gandhar K. Datar, Elmira Khabusheva, Archish Anand, Joshua Beale, Marwa Sadek, Chun-Wei David Chen, Evdokiia Potolitsyna, Nayara Sousa de Alcântara-Contessoto, Guangyuan Liu, Josephine De La Fuente, Christina Dollinger, Anna G. Guzman, Alejandra G. Martell, Katharina Wohlan, Abhishek Maiti, , Joshua A. Riback

This study shows that mutant NPM1 forms nuclear condensates called C-bodies, which are essential for leukemic gene expression and cell survival, and identifies them as potential therapeutic targets.

Cell · Nov 4, 2025Peer-reviewedBiophysics

Clonal dynamics and somatic evolution of haematopoiesis in mouse

Chiraag Deepak Kapadia, Nicholas Williams, Kevin J. Dawson, Caroline J. Watson, Matthew J. Yousefzadeh, Duy Tri Le, Kudzai Nyamondo, Sreeya Kodavali, Alex Cagan, Sarah M. Waldvogel, Xiaoyan Zhang, Josephine De La Fuente, Daniel A. Leongamornlert, Emily Mitchell, Marcus Alexander Florez, , Jyoti Nangalia

This study examines clonal dynamics and somatic evolution in mouse haematopoiesis, finding that stem cells accrue mutations at a rate similar to human progenitors and exhibit distinct age-related patterns.

Nature · Mar 5, 2025Peer-reviewedGenomics

Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress

Anja Karlstaedt, Heidi Vitrac, Rebecca Salazar, Benjamin D. Gould, Daniel Soedkamp, Weston R. Spivia, Koen Raedschelders, An Q Dinh, Anna G. Guzman, Lin Tan, Stavros Azinas, David J.R. Taylor, Walter B. Schiffer, Daniel McNavish, Helen B. Burks, , Heinrich Taegtmeyer

This study shows that D2-HG induces cachexia in mice by disrupting NAD+ homeostasis and autophagy, revealing metabolic vulnerabilities in skeletal muscle.

bioRxiv · Oct 13, 2020 · PreprintSystems Biology