Author
Harvard UniversityORCID 0000-0002-5125-9667Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Taral R. Lunavat, Lisa Nieland, Sanne M. van de Looij…·Koen Breyne
This study shows that delivering 4-1BBL via AAV enhances IL-12-induced anti-glioblastoma immunity in mouse models by boosting CD8 T cell activity and survival.
Shuqi Yun, Anil K. Chekuri, Jennifer Art…·Christiano R. R. Alves
This paper develops a CRISPR base editing strategy to correct the FD-causing mutation in human cells and mice, achieving up to 70% on-target correction and functional restoration.
Carina Henriques, Miguel Monteiro Lopes, Patrícia Maia Correia de Albuquerque…·Rui Jorge Nobre
This paper optimizes size exclusion chromatography (SEC) for isolating biologically active EV-AAVs for non-invasive brain gene delivery, showing higher recovery and transgene expression efficiency compared to differential ultracentrifugation.