Author

Seung‐Jae Lee

Seoul National UniversityORCID 0000-0002-5155-5335Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:matrix factorization· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andrew LeeiD· 1 shared Benedikt FriegiD· 1 shared Byung Chul JungiD· 1 shared Changyoun KimiD· 1 shared Christian DienemanniD· 1 shared Eliezer MasliahiD· 1 shared G.F. SchroederiD· 1 shared Inkyung JungiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Andrew LeeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Characterization of altered molecular mechanisms in Parkinson disease through cell type-resolved multi-omics analyses

Andrew Lee, Changyoun Kim, Seong-Wan Park, Kyoungho Jun, Junghyun Eom, Seung‐Jae Lee, Sun Ju Chung, Robert A. Rissman, Jongkyeong Chung, Eliezer Masliah, Inkyung Jung

This study identifies cell-type-specific dysregulated cis-regulatory elements and target genes in Parkinson's disease using multi-omic analyses of single-cell transcriptomes and epigenomes.

bioRxiv · Feb 13, 2022 · PreprintGenomics

α-Synuclein polymorphism determines oligodendroglial dysfunction

Benedikt Frieg, James A. Geraets, Timo Strohäker, Christian Dienemann, Panagiota Mavroeidi, Byung Chul Jung, Woojin Scott Kim, Seung‐Jae Lee, Maria Xilouri, Markus Zweckstetter, G.F. Schroeder

This study compares α-synuclein fibril structures from Parkinson's disease and Multiple System Atrophy patients, showing differences in their quaternary arrangement and effects on oligodendroglial cells.

bioRxiv · Jul 9, 2021 · PreprintNeuroscience