α-Synuclein polymorphism determines oligodendroglial dysfunction
Benedikt Frieg, James A. Geraets, Timo Strohäker, Christian Dienemann, Panagiota Mavroeidi, Byung Chul Jung, Woojin Scott Kim, Seung‐Jae Lee, Maria Xilouri, Markus Zweckstetter, G.F. Schroeder
This study compares α-synuclein fibril structures from Parkinson's disease and Multiple System Atrophy patients, showing differences in their quaternary arrangement and effects on oligodendroglial cells.
bioRxiv · Jul 9, 2021 · PreprintNeuroscience