Author

Karoline Holler

Max Delbrück CenterORCID 0000-0002-5159-9223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jan Philipp JunkeriD· 2 shared Alexander van OudenaardeniD· 1 shared Anika NeuschulziD· 1 shared Asher LichtigiD· 1 shared Balvir KunariD· 1 shared Bastiaan SpanjaardiD· 1 shared Brian LiiD· 1 shared Christopher R. D'Amato· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersDevelopmental Biology

Jan Philipp JunkerORCID

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2 papers

Recent·Most cited

Transcription factor induction of vascular blood stem cell niches in vivo

Elliott J. Hagedorn, Julie R. Perlin, Rebecca J. Freeman, Samuel J. Wattrus, Tianxiao Han, Clara Mao, Ji Wook Kim, Inés Fernández-Maestre, Madeleine L. Daily, Christopher R. D'Amato, Michael J. Fairchild, Raquel Riquelme, Brian Li, Dana A.V.E. Ragoonanan, Khaliun Enkhbayar, , Leonard Ira Zon

This study identifies transcription factors that induce vascular blood stem cell niches in vivo, enabling synthetic niche generation and potential therapeutic applications.

Developmental Cell · Apr 28, 2023Peer-reviewedDevelopmental Biology

Spatio-temporal mRNA dynamics in the early zebrafish embryo

Karoline Holler, Anika Neuschulz, Philipp Drewe-Boß, Janita Mintcheva, Bastiaan Spanjaard, Roberto Arsiè, Uwe Ohler, Markus Landthaler, Jan Philipp Junker

The paper uses spatial transcriptomics and single-cell RNA labeling to study mRNA localization and dynamics in early zebrafish embryos, revealing transport to primordial germ cells and evolutionary conservation.

Nature Communications · Jun 7, 2021Peer-reviewedSystems Biology