Samuel J. Wattrus

This study identifies kainate receptors' role in coordinating primitive hematopoiesis and hemogenic niche organization in zebrafish, showing their impact on hematopoietic stem cell development through endothelial Notch signaling.

This study identifies Ro5-3335 as a chemical that increases HSC clone number and clonal diversity by altering RUNX1 binding partners in zebrafish and mouse models.

This study identifies transcription factors that induce vascular blood stem cell niches in vivo, enabling synthetic niche generation and potential therapeutic applications.

The paper shows that macrophages interact with nascent blood stem cells in zebrafish embryos, influencing their survival and clonality through mechanisms involving calreticulin.