Author

Andrea Curtabbi

Spanish National Centre for Cardiovascular ResearchORCID 0000-0002-5185-4431Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

José Antonio Enrı́queziD· 2 shared Carmen Grueso-CortinaiD· 1 shared Carsten HopfiD· 1 shared Daniel Jiménez-BlascoiD· 1 shared Daniela Gerovska DiD· 1 shared Frank Thomas WunderlichiD· 1 shared Guangming WuiD· 1 shared Harmony C. Ketchum· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

José Antonio Enrı́quezORCID

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2 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedNov 18, 2024

TET3 regulates cellular terminal differentiation at the metabolic level

Isabel Mulet, Carmen Grueso-Cortina, Mireia Cortés-Cano…·Natàlia Tàpia

This study shows TET3 regulates terminal differentiation by affecting mitochondrial metabolic maturation and oxidative phosphorylation in intestinal epithelial cells.

6 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintAug 9, 2024

Uncoupling de novo pyrimidine biosynthesis from mitochondrial electron transport by ectopic expression of cytosolic DHODH

Andrea Curtabbi, R. Cortes, José Antonio Enrı́quez

This paper shows that expressing ScURA in mammalian cells allows pyrimidine biosynthesis independent of mitochondrial electron transport, enabling growth in uridine-deficient medium and improving mitochondrial disease models.

3 citations

humanexperimental assay

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