Sarah Masser

The cytosolic PRMT5-CDK4 complex impairs cell cycle kinase signaling

The paper identifies PRMT5-CDK4 complex formation as a non-enzymatic regulator of cell cycle signaling, showing it modulates CDK4 interactions and mimics CDK4 inhibition.

Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway

The paper studies the evolution of protein interactions in the Drosophila piRNA pathway, revealing conserved and co-evolved interactions that support evolutionary adaptation.

Mutational scanning pinpoints distinct binding sites of key ATGL regulators in lipolysis

The paper identifies switch mutations in ATGL that selectively disrupt interactions with specific regulatory proteins, linking these mutations to altered lipolysis activity and disease relevance.