Author

Alice Mac Kain

Centre National de la Recherche ScientifiqueORCID 0000-0002-5218-6690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Advait SubramanianiD· 1 shared Alan D. FrankeliD· 1 shared Alberto RomagnoniiD· 1 shared Alex J. CornishiD· 1 shared Alicia RichardsiD· 1 shared Almoatazbellah YoussefiD· 1 shared Benjamin J. PolaccoiD· 1 shared Beril TutuncuogluiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Advait SubramanianORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 15, 2026

Identification of non-covalent inhibitors for the atypical peroxiredoxin PRDX5 as a therapeutic strategy in malignant pleural mesothelioma

Josep Monserrat, Floriane Montanari, Victor Laurent…·Elodie Pronier

The paper identifies non-covalent inhibitors of PRDX5, a protein upregulated in MPM, through a machine learning guided pipeline and biochemical validation, suggesting it as a therapeutic target.

DOI 10.64898/2026.05.13.724787

humanproteomics

Systems BiologyNaturePeer-reviewedApr 30, 2020

✦ In-depth digest

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

David Ezra Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou…·Natalia Jura

Affinity-purification mass spectrometry of 26 SARS-CoV-2 proteins in HEK293T cells yields 332 high-confidence host interactions and 67 druggable human proteins with known compounds.

4,405 citationstop 1%

humanvirus