Deborah Kronenberg‐Versteeg

The paper identifies strategies to prevent transgene silencing during human pluripotent stem cell differentiation and introduces a robust vector construct.

This paper identifies a lncRNA, 3222401L13Rik/ENSG00000272070, that modulates microglial inflammatory responses through interaction with PU.1 and is reduced in Alzheimer's disease brains.

The paper introduces the Neurolipid Atlas, a lipidomics resource for neurodegenerative diseases, revealing that ApoE4 impairs astrocyte reactivity by promoting cholesterol ester accumulation.

The paper identifies CD72 as a regulator of microglial tiling through proteomic profiling and functional assays.

This study analyzes human dendritic spine morphology and density using a unique dataset and deep learning, revealing sex and tissue-specific differences and changes over time in culture.

The paper presents a multi-omics dataset for genetic subtypes of frontotemporal dementia to identify molecular mechanisms disrupted in the disease.

This study shows metformin can slow neurodegeneration features in mice, even in metabolically healthy individuals, by acting directly in the brain.

The paper identifies a novel miR-99b-5p-Zbp1 pathway in microglia that contributes to schizophrenia pathogenesis and suggests potential therapeutic strategies.

The paper identifies and characterizes a reference iPSC line, KOLF2.1J, for standardized use in collaborative studies across multiple differentiation protocols and assays.