Author

Charlotte E. Handford

University of CambridgeORCID 0000-0002-5245-8027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Magdalena Zernicka‐GoetziD· 3 shared Florian HollfelderiD· 2 shared Gianluca AmadeiiD· 2 shared Joachim De JongheiD· 2 shared Anna L. EllermanniD· 1 shared David B. MorseiD· 1 shared David Moore GloveriD· 1 shared Gregory M. FindlayiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersDevelopmental Biology

Magdalena Zernicka‐GoetzORCID

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3 papers

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedAug 8, 2023

spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content

Joachim De Jonghe, Tomasz S. Kamiński, David B. Morse…·Florian Hollfelder

spinDrop improves single-cell sequencing by reducing noise and increasing detection rates, enabling high-quality molecular atlases of mouse brain development and organogenesis.

62 citationstop 3%

mousescRNA-seq

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Developmental BiologybioRxivPreprintAug 1, 2022

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E. Handford, Joachim De Jonghe…·Magdalena Zernicka‐Goetz

This study shows that ETiX mouse embryos, generated from stem cells, develop through gastrulation and neurulation, forming anterior brain regions and a beating heart, and recapitulate natural embryonic development.

1 citation

mouseexperimental assay

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Developmental BiologySciencePeer-reviewedDec 10, 2020

Transcriptional control of apical protein clustering drives de novo cell polarity establishment in the early mouse embryo

Meng Zhu, Jake Cornwall-Scoones, Peizhe Wang…·Magdalena Zernicka‐Goetz

This study identifies transcriptional control and protein clustering as mechanisms driving cell polarity establishment in early mouse embryos.

115 citationstop 3%

mousebulk RNA-seq

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