Antoine Legras

Cis-aconitate therapy protects against influenza mortality by dual targeting of viral polymerase and ERK/AKT/NF-κB signaling

This study identifies cis-aconitate as a dual-action antiviral and anti-inflammatory agent that reduces influenza mortality in mice by targeting viral polymerase and ERK/AKT/NF-κB signaling.

A rapid agarose-free protocol for preparing human organotypic lung cultures to study respiratory virus infection and evaluate antivirals ex vivo

From tissue to subcellular level : imaging human precision-cut lung slices (PCLS) to gain insight into pandemic bacterial or viral infections

This paper describes a method to generate and image human precision-cut lung slices (PCLS) to study viral and bacterial infections, showing their utility for ex vivo pathogen research.