Author

Benjamin Gibert

Lyon 1 UniversitéORCID 0000-0002-5295-3124Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Cyril F. BourgeoisiD· 1 shared Didier AuboeufiD· 1 shared Franck MortreuxiD· 1 shared Jessica Valat· 1 shared Matéo Bazire· 1 shared Nicolas Fontrodona· 1 shared Nicolas RamaiD· 1 shared Valentine Clerc· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Cyril F. BourgeoisORCID

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1 paper

Recent·Most cited

The MYCN oncoprotein and helicases DDX17 and DDX5 have opposite effects on the production of chimeric transcripts in neuroblastoma cells

Valentine Clerc, Jessica Valat, Xavier Grand, Nicolas Fontrodona, Matéo Bazire, Nicolas Rama, Didier Auboeuf, Benjamin Gibert, Franck Mortreux, Cyril F. Bourgeois

This study shows that MYCN and helicases DDX17/DDX5 have opposing roles in transcription termination and chimeric transcript production in neuroblastoma, with MYCN inhibiting helicase activity and promoting harmful RNA molecules.

bioRxiv · Feb 5, 2024 · PreprintMolecular Biology