Matéo Bazire

The MYCN oncoprotein and helicases DDX17 and DDX5 have opposite effects on the production of chimeric transcripts in neuroblastoma cells

This study shows that MYCN and helicases DDX17/DDX5 have opposing roles in transcription termination and chimeric transcript production in neuroblastoma, with MYCN inhibiting helicase activity and promoting harmful RNA molecules.

Gene-to-Gene Coordinated Regulation of Transcription and Alternative splicing by 3D Chromatin Remodeling upon NF-κB activation

This study investigates how NF-κB activation through HTLV-1 Tax reorganizes 3D chromatin to coordinate transcription and alternative splicing of target genes.

Multi-omics comparison of malignant and normal uveal melanocytes reveals novel molecular features of uveal melanoma.

The paper uses multi-omics analysis to compare malignant and normal uveal melanocytes, identifying genomic instability and a BAP1 promoter deletion as key features of uveal melanoma.