Matthew R. Bersi

This study investigates sex-specific tricuspid valve leaflet remodeling in an ovine model of functional tricuspid regurgitation, revealing distinct structural, mechanical, and transcriptional responses across sexes and castration status.

This study shows that adaptive immunity influences regional aortic remodeling in hypertension by modulating perivascular adipose tissue plasticity and immune-metabolic interactions.

This study shows that macrophages in Notch1+/- mice promote osteogenic calcification in aortic valves through STAT3 splicing changes and increased recruitment and polarization.

This study shows that blocking CDH11 reduces inflammation-driven fibrosis and improves cardiac function after myocardial infarction in mice.

This study shows FAK regulates focal adhesion dynamics during myofibril assembly in cardiomyocytes, essential for myofibril maturation and force balance.