Xin Zhou

This study shows that micafungin exposure selects for multidrug resistance in C. lusitaniae through mutations in ERG3, leading to sterol reprogramming and cell wall remodeling.

This study analyzes genomic variation in serial Candida albicans isolates from patients, identifying aneuploidy, polyploidy, and loss of heterozygosity as factors driving antifungal drug tolerance.

This study identifies ERG251 mutations that confer azole tolerance and pleiotropic effects on stress responses and filamentation in C. albicans.