Nívea Pereira de Sá

This study shows that micafungin exposure selects for multidrug resistance in C. lusitaniae through mutations in ERG3, leading to sterol reprogramming and cell wall remodeling.

This study shows how azole resistance in Candida albicans evolves through copy number variation followed by KSR1 loss of heterozygosity, resulting in a >500-fold resistance increase.

This study identifies mitochondrial metabolic changes in old Cryptococcus neoformans cells that drive fluconazole tolerance through increased ergosterol synthesis and ABC transporter upregulation.

This study identifies ERG251 mutations that confer azole tolerance and pleiotropic effects on stress responses and filamentation in C. albicans.