Author

Takashi Moriguchi

Tohoku Medical and Pharmaceutical UniversityORCID 0000-0002-5341-8932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Aki MurashimaiD· 1 shared Andrew D. WhiteiD· 1 shared Chia-Jui Ku· 1 shared Chikako YokoyamaiD· 1 shared Daisuke MatsumaruiD· 1 shared Emily SchneideriD· 1 shared Greggory MyersiD· 1 shared James Douglas EngeliD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Aki MurashimaORCID

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2 papers

Recent·Most cited

The sympathoadrenal contribution to inferior vena cava formation

Aki Murashima, Daisuke Matsumaru, Takashi Moriguchi, Yuichi Shima, Miki Inoue, Chikako Yokoyama, Ken-ichirou Morohashi, Yoshiaki Kubota, Takatoshi Ueki, Jiro Hitomi, Sumio Isogai

This study identifies a sympathoadrenal origin for the renal segment of the inferior vena cava in mice, challenging the classical mesonephros-centric model and explaining anatomical variations.

bioRxiv · Aug 1, 2025 · PreprintDevelopmental Biology

The epigenetic eraser LSD1 lies at the apex of a reversible erythroid to myeloid cell fate decision

Lei Yu, Greggory Myers, Chia-Jui Ku, Emily Schneider, Yu Wang, Sharon A Singh, Natee Jearawiriyapaisarn, Andrew D. White, Takashi Moriguchi, Rami N. Khoriaty, Masayuki P. Yamamoto, M. Geoffrey Rosenfeld, Julien Pedron, John Hackett Bushweller, Kim-Chew Lim, James Douglas Engel

This study shows that LSD1 promotes erythropoiesis by repressing myeloid fate, and inhibiting myeloid factors reverses lineage conversion caused by LSD1 inactivation in mice and human HSPC.

bioRxiv · Jan 13, 2021 · PreprintDevelopmental Biology