Author

Kim-Chew Lim

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Greggory MyersiD· 3 shared James Douglas EngeliD· 3 shared Lei YuiD· 2 shared Natee JearawiriyapaisarniD· 2 shared Andrew D. WhiteiD· 1 shared Anne B. Vojtek· 1 shared Anthony B. FirulliiD· 1 shared Boksik ChaiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersDevelopmental Biology

Greggory MyersORCID

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4 papers

Recent·Most cited

GATA3 is essential for separating patterning domains during facial morphogenesis

Makoto Abe, Timothy C. Cox, Anthony B. Firulli, Stanley M. Kanai, Jacob Dahlka, Kim-Chew Lim, James Douglas Engel, David E. Clouthier

This study shows that Gata3 disruption in mouse embryos causes facial abnormalities due to impaired separation of mandibular and maxillary domains during development.

Development · Aug 12, 2021Peer-reviewedDevelopmental Biology

The epigenetic eraser LSD1 lies at the apex of a reversible erythroid to myeloid cell fate decision

Lei Yu, Greggory Myers, Chia-Jui Ku, Emily Schneider, Yu Wang, Sharon A Singh, Natee Jearawiriyapaisarn, Andrew D. White, Takashi Moriguchi, Rami N. Khoriaty, Masayuki P. Yamamoto, M. Geoffrey Rosenfeld, Julien Pedron, John Hackett Bushweller, Kim-Chew Lim, James Douglas Engel

This study shows that LSD1 promotes erythropoiesis by repressing myeloid fate, and inhibiting myeloid factors reverses lineage conversion caused by LSD1 inactivation in mice and human HSPC.

bioRxiv · Jan 13, 2021 · PreprintDevelopmental Biology

GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126

Md. Riaj Mahamud, Xin Geng, Yen‐Chun Ho, Boksik Cha, Yuenhee Kim, Jing Ma, Lijuan Chen, Greggory Myers, Sally Ann Camper, Debbie J. Mustacich, Marlys Hearst Witte, Dongwon Choi, Young-Kwon Hong, Hong Chen, Gaurav K. Varshney, , R. Sathish Srinivasan

This study identifies GATA2's role in maintaining lymphatic endothelial cell junctions and valve morphogenesis through regulation of miR-126.

Development · Jan 1, 2019Peer-reviewedDevelopmental Biology

BAP1 deubiquitinase is a potent repressor of fetal hemoglobin biosynthesis

Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-Francois M. Rual, James Douglas Engel

The paper identifies BAP1 as a key repressor of fetal hemoglobin biosynthesis by maintaining NCoR1 at the β-globin locus and shows its inhibition increases γ-globin synthesis.

bioRxiv · Jun 13, 2018 · PreprintDevelopmental Biology