Rami N. Khoriaty

This study identifies aspartate transaminases GOT1 and GOT2 as critical for erythropoiesis by linking metabolism to epigenetic regulation, revealing a novel role in blood development.

The paper identifies a lipid metabolism defect as a contributor to variable anemia in Diamond Blackfan anemia syndrome using a murine model and transcriptomic analysis.

The paper shows that SAR1A and SAR1B paralogs have overlapping functions in mice, with SAR1A compensating for SAR1B deficiency.

This paper describes a novel Rpl5 mutation in mice that models Diamond Blackfan Anemia with variable penetrance and anemia remission.

This study shows that LSD1 promotes erythropoiesis by repressing myeloid fate, and inhibiting myeloid factors reverses lineage conversion caused by LSD1 inactivation in mice and human HSPC.