Author

Xiyun Ye

Massachusetts Institute of TechnologyORCID 0000-0002-5342-9244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrei LoasiD· 2 shared Bradley L. PenteluteiD· 2 shared Dan EatoniD· 2 shared John C. K. WangiD· 2 shared Peiyuan ZhangiD· 2 shared Aaron H. NileiD· 1 shared Amirhossein MafiiD· 1 shared Anthony J. QuartararoiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Andrei LoasORCID

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2 papers

Recent·Most cited

Branched multimeric peptides as affinity reagents for detection of α-Klotho protein

Xiyun Ye, Peiyuan Zhang, John C. K. Wang, Corey L. Smith, Silvino Sousa, Andrei Loas, Dan Eaton, Magdalena Preciado López, Bradley L. Pentelute

This paper develops branched multimeric peptides that bind α-Klotho with high affinity and selectivity, enabling its detection and labeling in biological systems.

Angewandte Chemie · Mar 9, 2023Peer-reviewedMolecular Biology

Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6

Xiyun Ye, Peiyuan Zhang, Jason Tao, John C. K. Wang, Amirhossein Mafi, Nathalie M. Grob, Anthony J. Quartararo, Hannah T. Baddock, Leanne Jade G. Chan, Fiona Elizabeth McAllister, Ian T. Foe, Andrei Loas, Dan Eaton, Qi Hao, Aaron H. Nile, Bradley L. Pentelute

The paper designs a covalent peptide inhibitor, reactide, targeting the HPV16 E6-E6AP interaction to prevent p53 degradation.

Chemical Science · Jan 1, 2023Peer-reviewedMolecular Biology