Author

Aaron H. Nile

Calico Life SciencesORCID 0000-0002-7370-8769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Fiona Elizabeth McAllisteriD· 2 shared Hannah T. BaddockiD· 2 shared Aleksandr GauniD· 1 shared Alfred Millett-Sikking· 1 shared Amirhossein MafiiD· 1 shared Andrei LoasiD· 1 shared Andrew G. York· 1 shared Anthony J. QuartararoiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersCell Biology

Fiona Elizabeth McAllisterORCID

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Author profile →

3 papers

Recent·Most cited

Triplet tumbling microscopy enables in situ quantification of protein complex assembly and dynamics

Julia R. Lazzari-Dean, Alfred Millett-Sikking, Prashant Rao, Zena D. Jensvold, Hannah T. Baddock, María Ingaramo, Aaron H. Nile, Andrew G. York, Magdalena Preciado López

The paper introduces triplet tumbling microscopy (TTM) to quantify protein complex assembly and dynamics in living cells by measuring rotational diffusion.

bioRxiv · Jun 15, 2026 · PreprintBiophysics

Site-specific combinatorial ubiquitination drives the targeted degradation of plasma membrane proteins

Niclas Olsson, Aleksandr Gaun, Sammy Villa, Katrina L. Jackson, Mark E. Fitzgerald, Fiona Elizabeth McAllister, David Stokoe, Aaron H. Nile, Kirill Bersuker

This study identifies ubiquitination sites on RTKs that mediate their degradation via CRLs and shows that multiple ubiquitination sites are required for effective degradation.

bioRxiv · May 27, 2026 · PreprintCell Biology

Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6

Xiyun Ye, Peiyuan Zhang, Jason Tao, John C. K. Wang, Amirhossein Mafi, Nathalie M. Grob, Anthony J. Quartararo, Hannah T. Baddock, Leanne Jade G. Chan, Fiona Elizabeth McAllister, Ian T. Foe, Andrei Loas, Dan Eaton, Qi Hao, Aaron H. Nile, Bradley L. Pentelute

The paper designs a covalent peptide inhibitor, reactide, targeting the HPV16 E6-E6AP interaction to prevent p53 degradation.

Chemical Science · Jan 1, 2023Peer-reviewedMolecular Biology