Hengye Chen

The paper shows that cohesin facilitates nucleosome invasion by transcription factors, even in the absence of chromatin remodeling or replication.

The paper characterizes native nucleosome-positioning elements in yeast and shows they can be used to study nucleosome repositioning by transcription factors and chromatin remodelers.

This study investigates how budding yeast pioneer transcription factors bind and dissociate from nucleosomal DNA, showing they compensate for reduced binding by increasing dwell time, similar to human pioneer factors.