Author

Chloe Rybicki-Kler

University of MichiganORCID 0000-0002-5359-088XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

Isla A. W. BrooksiD· 3 shared Izabela Jedrasiak‐Cape· 3 shared Omar J. AhmediD· 3 shared Tyler G. EkinsiD· 3 shared Sameer KailasaiD· 2 shared Alan C. RuppiD· 1 shared Ellen K.W. Brennan· 1 shared Ethan Donoho· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Isla A. W. BrooksORCID

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3 papers

Recent·Most cited

Unique Transcriptomic Cell Types of the Granular Retrosplenial Cortex are Preserved Across Mice and Rats Despite Dramatic Changes in Key Marker Genes

Isla A. W. Brooks, Izabela Jedrasiak‐Cape, Chloe Rybicki-Kler, Tyler G. Ekins, Omar J. Ahmed

The paper identifies evolutionarily conserved cell types in the granular retrosplenial cortex across mice and rats, despite differences in marker genes.

Journal of Neuroscience · Oct 13, 2025Peer-reviewedNeuroscience

Cell-type-specific cholinergic control of granular retrosplenial cortex with implications for angular velocity coding across brain states

Izabela Jedrasiak‐Cape, Chloe Rybicki-Kler, Isla A. W. Brooks, Megha Ghosh, Ellen K.W. Brennan, Sameer Kailasa, Tyler G. Ekins, Alan C. Rupp, Omar J. Ahmed

The paper identifies a distinct RSG neuron subtype, LR neurons, that lacks persistent firing in response to cholinergic agonists, enabling consistent angular head velocity computation across brain states.

Progress in Neurobiology · Jul 15, 2025Peer-reviewedNeuroscience

Cellular rules underlying psychedelic control of prefrontal pyramidal neurons

Tyler G. Ekins, Isla A. W. Brooks, Sameer Kailasa, Chloe Rybicki-Kler, Izabela Jedrasiak‐Cape, Ethan Donoho, George A. Mashour, Jason C. Rech, Omar J. Ahmed

This study shows that psychedelics suppress intrinsic excitability of prefrontal pyramidal neurons via M-current channels, independent of 5-HT2AR activation, and reduces working memory timespan.

bioRxiv · Oct 20, 2023 · PreprintNeuroscience