Tyler G. Ekins

Unique Transcriptomic Cell Types of the Granular Retrosplenial Cortex are Preserved Across Mice and Rats Despite Dramatic Changes in Key Marker Genes

The paper identifies evolutionarily conserved cell types in the granular retrosplenial cortex across mice and rats, despite differences in marker genes.

Cell-type-specific cholinergic control of granular retrosplenial cortex with implications for angular velocity coding across brain states

The paper identifies a distinct RSG neuron subtype, LR neurons, that lacks persistent firing in response to cholinergic agonists, enabling consistent angular head velocity computation across brain states.

Psychedelic enhancement of flexible learning weeks after a single dose

This paper shows that a single dose of 25CN-NBOH improves cognitive flexibility in mice weeks later, using a complex reversal learning task.

Cellular rules underlying psychedelic control of prefrontal pyramidal neurons

This study shows that psychedelics suppress intrinsic excitability of prefrontal pyramidal neurons via M-current channels, independent of 5-HT2AR activation, and reduces working memory timespan.

Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

The paper examines LIS1 mutation effects on PV+INTs in mouse hippocampus, identifying a non-canonical intermediate spiking subset linked to seizures.

Aberrant sorting of hippocampal complex pyramidal cells in Type I Lissencephaly alters topological innervation

This study examines synaptic circuitry formation in a mouse model of Type I Lissencephaly, identifying mispositioned calbindin-expressing principal cells and altered connectivity patterns.