Author

Jason C. Rech

University of MichiganORCID 0000-0002-6822-5236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:zebrafish· 1

Frequent Co-Authors

Allison C. FergusoniD· 1 shared Chloe Rybicki-KleriD· 1 shared Clayton J. HabigeriD· 1 shared David A. HanaueriD· 1 shared David Wu· 1 shared Ethan Donoho· 1 shared George A. MashouriD· 1 shared Hongyu Su· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

Allison C. FergusonORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

FDA-approved drug repurposing in zebrafish identifies thyroid hormone and other compounds as potential antithrombotics

Murat Yaman, Hongyu Su, Jacqueline K. Lee, Allison C. Ferguson, Katherine M Sowell, Jenny Xun, David Wu, Clayton J. Habiger, David A. Hanauer, Martin C. Clasby, Jason C. Rech, Jordan A. Shavit

This study uses zebrafish to screen FDA-approved drugs for antithrombotic effects, identifying thyroid hormone and others as potential treatments for VTE subtypes.

bioRxiv · Sep 23, 2025 · PreprintPharmacology & Toxicology

Cellular rules underlying psychedelic control of prefrontal pyramidal neurons

Tyler G. Ekins, Isla A. W. Brooks, Sameer Kailasa, Chloe Rybicki-Kler, Izabela Jedrasiak‐Cape, Ethan Donoho, George A. Mashour, Jason C. Rech, Omar J. Ahmed

This study shows that psychedelics suppress intrinsic excitability of prefrontal pyramidal neurons via M-current channels, independent of 5-HT2AR activation, and reduces working memory timespan.

bioRxiv · Oct 20, 2023 · PreprintNeuroscience