Author
Lei Tan
Shanghai Veterinary Research InstituteORCID 0000-0002-5362-1359Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 31 mutual co-author links4 papers
Recent·Most cited
- Cell BiologybioRxivPreprintDOI 10.64898/2026.10.25.761721
- MicrobiologybioRxivPreprint
Coronavirus papain-like protease antagonizes innate immunity by cleaving Importin α1 to disrupt nuclear transport
王皆欢, Wenxiang Xue, Sun YingJie…·Ying Liao
This paper identifies that coronavirus PLpro-TM cleaves Importin α1 to disrupt nuclear transport and suppress antiviral immunity, revealing a conserved immune evasion strategy across coronaviruses.
DOI 10.64898/2026.07.17.739146 - MicrobiologyPLoS PathogensPeer-reviewed
Coronavirus Nucleocapsid Protein Enhances the binding of p-PKCα to RACK1: Implications for Inhibition of Nucleocytoplasmic Trafficking and Suppression of the Innate Immune Response
Wenxiang Xue, Hongyan Chu, Jiehuang Wang…·Ying Liao
This study identifies how the coronavirus N protein disrupts nucleocytoplasmic trafficking and suppresses the innate immune response by promoting RACK1-PKC interaction and NUP62 phosphorylation.
14 citations - MicrobiologybioRxivPreprint
Infectious bronchitis virus attaches to lipid rafts and enters cells via clathrin mediated endocytosis
Huan Wang, Yingjie Sun, Xiang Mao…·Ying Liao
This study identifies the molecular mechanisms of infectious bronchitis virus (IBV) entry, showing it attaches to lipid rafts and enters via clathrin-mediated endocytosis, followed by endosomal trafficking and membrane fusion.
DOI 10.1101/352898