Yingjie Sun

This study identifies DAZAP2 as a pan-coronavirus restriction factor that inhibits viral entry and genomic replication, with physiological relevance confirmed in mouse models and human cells.

The paper introduces POST-IT, a non-diffusive proximity tagging system for identifying target proteins in live cells and zebrafish embryos, and demonstrates its application in discovering new drug targets.

This study identifies how the coronavirus N protein disrupts nucleocytoplasmic trafficking and suppresses the innate immune response by promoting RACK1-PKC interaction and NUP62 phosphorylation.

This study identifies the molecular mechanisms of infectious bronchitis virus (IBV) entry, showing it attaches to lipid rafts and enters via clathrin-mediated endocytosis, followed by endosomal trafficking and membrane fusion.