Michael J. Goard

Disrupted Brain Organoid Circuitry, Structural Organization, and Spine Morphology in 7q11.23 Copy Number Variant Syndromes

This study investigates how 7q11.23 copy number variations disrupt brain organoid development, showing structural and functional abnormalities in neural circuits and spine morphology.

The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding

This study investigates how the estrous cycle affects hippocampal spine dynamics, dendritic processing, and spatial coding in female mice using in vivo imaging.

Robust variability of grid cell properties within individual grid modules enhances encoding of local space

The paper analyzes grid cell properties in the medial entorhinal cortex and finds small but robust variability within modules, which improves spatial encoding.

Coregistration of heading to visual cues in retrosplenial cortex

The paper investigates how retrosplenial cortex neurons in mice coregister visual and thalamic signals to align heading responses with environmental landmarks.

Differential Stability of Task Variable Representations in Retrosplenial Cortex

The paper examines stability differences in task variable representations in retrosplenial cortex, finding context and trial outcome are more stable than motor choice.

Long-term Transverse Imaging of the Hippocampus with Glass Microperiscopes

The paper develops a method for two-photon imaging of the transverse hippocampal plane in awake mice, enabling tracking of dendritic dynamics and characterization of spatial information distribution.

Inhibiting retinoic acid mitigates vision loss in a mouse model of retinal degeneration

The paper shows that inhibiting retinoic acid (RA) reduces retinal ganglion cell (RGC) hyperactivity and improves image detection in a mouse model of retinal degeneration.

Stimulus-dependent representational drift in primary visual cortex

This study shows that neural representations in mouse V1 are stable for artificial stimuli but drift for naturalistic stimuli over weeks, suggesting stimulus-dependent stability linked to circuit architecture.

A distributed circuit for associating environmental context to motor choice in retrosplenial cortex

The paper investigates the role of retrosplenial cortex in linking environmental contexts to motor choices in mice, finding that RSC activity is critical for this association.

Distributed and Retinotopically Asymmetric Processingn of Coherent Motion in Mouse Visual Cortex

The paper investigates motion processing in mouse visual cortex, finding heterogeneous responses across areas and retinotopic asymmetry in motion sensitivity.

Task-Dependent Representations Of Stimulus And Choice In Mouse Parietal Cortex

The paper investigates how mouse posterior parietal cortex (PPC) encodes visual stimuli and task-related choices, finding that PPC responses are task-dependent and heterogeneous compared to primary visual cortex (V1).